%0 Journal Article
%T The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
%A Andrea M Hujer
%A Ashley Boshe
%A Courtney L Luterbach
%A David van Duin
%A Eric Cober
%A Heather I Henderson
%A Keith S Kaye
%A Kristine M Hujer
%A Richard R Watkins
%A Robert A Bonomo
%A Robert A Salata
%A Robert C Kalayjian
%A Sandra S Richter
%A Scott Evans
%A Susan D Rudin
%A T Nicholas Domitrovic
%A Vance G Fowler
%A Jr.
%A Yohei Doi
%J Archive of "Open Forum Infectious Diseases".
%D 2019
%R 10.1093/ofid/ofy351
%X In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of tested CRE, only 29% were susceptible to TMP-SMX. Development of resistance further limits the use of TMP-SMX in CRE infections
%K antimicrobial resistance
%K carbapenem-resistant Enterobacteriaceae
%K Klebsiella pneumonia
%K trimethoprim-sulfamethoxazole
%K urinary tract infection
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324543/