%0 Journal Article
%T Symptomatic cerebrospinal fluid HIV-1 escape in two patients on second-line antiretroviral therapy in Uganda
%A Andrea Calcagno
%A Barbara Castelnouvo
%A Eva Laker
%A Ivan Segawa
%A Kenneth Ssebambulidde
%A Mohammed Lamorde
%A Noeline Nakasujja
%J Archive of "Oxford Medical Case Reports".
%D 2019
%R 10.1093/omcr/omy132
%X Two HIV-infected individuals on second-line atazanavir-based antiretroviral therapy presented with neuropsychiatric symptoms. Cerebrospinal fluid HIV RNA was higher than plasma HIV RNA and antiretroviral regimens¡¯ optimization led to prompt resolution of symptoms in one. Patients on second-line atazanavir-based antiretroviral therapy with documented previous treatment failure may be at risk of symptomatic cerebrospinal fluid escape
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380528/