%0 Journal Article %T A longitudinal investigation into cognition and disease progression in spinocerebellar ataxia types 1, 2, 3, 6, and 7 %A Amy Moriarty %A Arron Cook %A Helen Hunt %A Lisa Cipolotti %A Matthew E. Adams %A Paola Giunti %J Archive of "Orphanet Journal of Rare Diseases". %D 2016 %R 10.1186/s13023-016-0447-6 %X The natural history of clinical symptoms in the spinocerebellar ataxias (SCA)s has been well characterised. However there is little longitudinal data comparing cognitive changes in the most common SCA subtypes over time. The present study provides a preliminary longitudinal characterisation of the clinical and cognitive profiles in patients with SCA1, SCA2, SCA3, SCA6 and SCA7, with the aim of elucidating the role of the cerebellum in cognition %K Ataxia %K Spinocerebellar ataxia %K Cognition %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917932/