%0 Journal Article %T Impact of orphan drugs on Latvian budget %A Dainis Krievins %A Konstantins Logviss %A Santa Purvina %J Archive of "Orphanet Journal of Rare Diseases". %D 2016 %R 10.1186/s13023-016-0434-y %X Number of orphan medicinal products on the market and number of rare disease patients, taking these usually expensive products, are increasing. As a result, budget impact of orphan drugs is growing. This factor, along with the cost-effectiveness of orphan drugs, is often considered in the reimbursement decisions, directly affecting accessibility of rare disease therapies. The current study aims to assess the budget impact of orphan drugs in Latvia %K Orphan drugs %K Budget impact %K Expenditure %K Reimbursement %K Latvia %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864910/