%0 Journal Article
%T Suppl-1, M4: Genetics in Keratoconus ¨C What is New?
%A G¨šnther Grabner
%A Herbert Reitsamer
%A Josef Ruckhofer
%A Marie Dietrich
%A Sarah Moussa
%J Archive of "The Open Ophthalmology Journal".
%D 2017
%R 10.2174/1874364101711010201
%X Keratoconus is characterized as a bilateral, progressive, non-inflammatory thinning of the cornea resulting in blurred vision due to irregular astigmatism. Keratoconus has a multifactorial etiology, with multiple genetic and environmental components contributing to the disease pathophysiology. Several genomic loci and genes have been identified that highlight the complex molecular etiology of this disease
%K Keratoconus
%K Genetics
%K Environmental risk factors
%K Non-inflammatory
%K Irregular astigmatism
%K Genomic loci
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585456/