%0 Journal Article %T Why We should Assess Patients¡¯ Expectations in Clinical Trials %A Aziz Shaibani %A Elisa Frisaldi %A Fabrizio Benedetti %J Archive of "Pain and Therapy". %D 2017 %R 10.1007/s40122-017-0071-8 %X Most of the analgesic clinical trials have failed to succeed over the past years because of the occurrence of large placebo responses. Patients¡¯ expectations about the therapeutic benefit represent a major determinant of the placebo response. Therefore, assessing patients¡¯ expectations should become the rule in any clinical trial. This would allow us to better interpret therapeutic outcomes when comparing placebo and verum groups %K Clinical trial %K Expectation %K Placebo effect %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447548/