%0 Journal Article %T Original research article: Impact of early treatment with intravenous vasodilators and blood pressure reduction in acute heart failure %A Andrew Xanthopoulos %A Eiichi Akiyama %A Keisuke Kida %A Kitae Kim %A Masayoshi Yamamoto %A Ryosuke Murai %A Satoshi Suzuki %A Shogo Oishi %A Shuichiro Kaji %A Takafumi Yamane %A Takahiro Okumura %A Takeshi Kitai %A W H Wilson Tang %A Yutaka Furukawa %A Yuya Matsue %J Archive of "Open Heart". %D 2018 %R 10.1136/openhrt-2018-000845 %X Although vasodilators are used in acute heart failure (AHF) management, there have been no clear supportive evidence regarding their routine use. Recent European guidelines recommend systolic blood pressure (SBP) reduction in the range of 25% during the first few hours after diagnosis. This study aimed to examine clinical and prognostic significance of early treatment with intravenous vasodilators in relation to their subsequent SBP reduction in hospitalised AHF %K heart failure %K heart failure treatment %K vasodilators %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045748/