%0 Journal Article %T Exposure to Low Dose of Cinnabar (a Naturally Occurring Mercuric Sulfide (HgS)) Caused Neurotoxicological Effects in Offspring Mice %A Chun-Fa Huang %A Chuan-Jen Hsu %A Shing-Hwa Liu %A Shoei-Yn Lin-Shiau %J Journal of Biomedicine and Biotechnology %D 2012 %I Hindawi Publishing Corporation %R 10.1155/2012/254582 %X Cinnabar, a naturally occurring mercuric sulfide (HgS), has long been used in Chinese mineral medicine for more than 2000 years. Although mercury is well-known for its toxicity, whether cinnabar induces neurotoxicity, especially in infants and children, is unknown. The purpose of this study was to explore the neurotoxic effects of low-dose of cinnabar (10 mg/kg/day) on developing mice. The results revealed neurobehavioral defects in F1-C-Cin group, which were associated with Hg accumulation, increased NOx levels in whole blood, and Na %U http://www.hindawi.com/journals/biomed/2012/254582/