%0 Journal Article %T Root Canal Irrigation: Chemical Agents and Plant Extracts Against Enterococcus faecalis %A Adriano Casaglia %A Letizia Borzini %A Loredana Cerroni %A Paolo De Dominicis %A Roberta Cond¨° %J Archive of "The Open Dentistry Journal". %D 2016 %R 10.2174/1874210601610010692 %X There are various microorganisms related to intra and extra-radicular infections and many of these are involved in persistent infections. Bacterial elimination from the root canal is achieved by means of the mechanical action of instruments and irrigation as well as the antibacterial effects of the irrigating solutions. Enterococcus faecalis can frequently be isolated from root canals in cases of failed root canal treatments. Antimicrobial agents have often been developed and optimized for their activity against endodontic bacteria. An ideal root canal irrigant should be biocompatible, because of its close contact with the periodontal tissues during endodontic treatment. Sodium hypoclorite (NaOCl) is one of the most widely recommended and used endodontic irrigants but it is highly toxic to periapical tissues %K Root canal irrigation %K Phytotherapic substances %K Enterococcus faecalis %K Essential oil %K Plant extracts %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299586/