%0 Journal Article %T High attack frequency in patients with angioedema due to C1-inhibitor deficiency is a major determinant in switching to home therapy: a real-life observational study %A Alessandro Barbarino %A Angelica Petraroli %A Arturo Genovese %A Carmela Gravante %A Gianni Marone %A Giuseppe Spadaro %A Maria Bova %A Massimo Triggiani %A Veronica Squeglia %J Archive of "Orphanet Journal of Rare Diseases". %D 2016 %R 10.1186/s13023-016-0518-8 %X Hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) is characterized by recurrent attacks of swelling that affect various body sites. Such attacks are a frequent cause of visits to the emergency department and are often treated in the hospital. In recent years, self-administration of C1-inhibitor (C1-INH) concentrates at home has become an increasingly used option, with a positive impact on patient outcomes and quality of life %K C1-inhibitor deficiency %K Hereditary angioedema %K C1-inhibitor concentrates %K Icatibant %K Home therapy %K Self-administration %K Attack frequency %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043538/