%0 Journal Article
%T MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9
%A Dominika Brchnelova
%A Igor Kiss
%A Irene Gutierrez-Garcia
%A Jana Halamkova
%A Jana Merhautova
%A Jos¨¦ Garcia-Solano
%A Katerina Slaba
%A Lenka Radova
%A Marek Svoboda
%A Ondrej Slaby
%A Pablo Conesa-Zamora
%A Petra Vychytilova-Faltejskova
%A Regina Demlova
%A Rostislav Vyzula
%A Tana Machackova
%J Archive of "Oncogenesis".
%D 2017
%R 10.1038/s41389-017-0006-6
%X a Expression levels of miR-215-5p are significantly decreased in CRC tissues compared with healthy adjacent tissues (P£¿<£¿0.0001; Czech cohort). b Expression levels of miR-215-5p are significantly decreased in CRC tissues compared with healthy adjacent tissues (P£¿<£¿0.0001; Spain cohort). c Expression of miR-215-5p significantly decreases with advanced clinical stage (P£¿<£¿0.0001; Czech cohort). d Expression of miR-215-5p significantly decreases with advanced clinical stage (P£¿=£¿0.0185; Spain cohort). e Low levels of miR-215-5p correlate with shorter OS of Czech CRC patients (P£¿=£¿0.0024). f Low levels of miR-215-5p correlate with shorter OS of Spain CRC patients (P£¿=£¿0.0111). OS overall surviva
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868056/