%0 Journal Article
%T hMOF reduction enhances radiosensitivity through the homologous recombination pathway in non-small-cell lung cancer
%A Guang Li
%A Guang-Wei Tian
%A Ling-Rong Tang
%A Nan Li
%J Archive of "OncoTargets and therapy".
%D 2019
%R 10.2147/OTT.S192568
%X Human males absent on the first (hMOF) is a histone acetyltransferase (HAT) and is responsible for acetylating histone H4 at lysine 16 (H4K16). Recent studies have indicated that hMOF is overexpressed in non-small-cell lung cancer (NSCLC) as an oncogene. The aim of this study is to profile the prognostic roles of hMOF in patients with unresectable stage III NSCLC undergoing definitive radiotherapy (RT) and in the radiosensitivity of human NSCLC cells
%K prognosis
%K NSCLC
%K hMOF
%K radiosensitivity
%K HATs
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485037/