%0 Journal Article
%T 636. The Hepcidin-25 and Iron Kinetics During the Acute Phase of Systemic Infection
%J Archive of "Open Forum Infectious Diseases".
%D 2018
%R 10.1093/ofid/ofy210.643
%X Hepcidin-25, a central regulator of iron metabolism, can decrease serum iron levels by inhibiting the iron transporter ferroportin. Production of hepcidin-25 in hepatocytes is tightly regulated by various stimulations and is promoted by inflammation via the IL-6 pathway. The role of hepcidin-25 in acute infections has not been fully understood; therefore, we investigated the hepcidin and iron kinetics during the acute phase of systemic infection
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253969/