%0 Journal Article
%T MiR-206 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting the MUC1 gene
%A Jianchao Wang
%A Min Deng
%A Qizhi Wang
%A Xiaodong Chen
%A Yiyu Qin
%J Archive of "OncoTargets and therapy".
%D 2019
%R 10.2147/OTT.S180021
%X MicroRNAs (miRNAs) can regulate the post-transcriptional level of gene expression. It has been documented that downregulation of miR-206 is significant in human gastric cancer (GC), whereas its role in GC cell biological behaviors, including proliferation, migration, and invasion, has not been thoroughly investigated. MiR-206 levels have a negative association with lymph node metastasis and tumor invasion, and patients with higher miR-206 expression have better prognoses. Functional studies demonstrated that miR-206 overexpression significantly suppresses GC cell proliferation, migration, and invasion, and induces apoptosis in vitro
%K miR-206
%K MUC1
%K gastric cancer
%K metastasis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355168/