%0 Journal Article %T Supplementation with a Polyphenol-Rich Extract, PerfLoad£¿, Improves Physical Performance during High-Intensity Exercise: A Randomized, Double Blind, Crossover Trial %A Caroline Laurent %A Cindy Romain %A Cristian Mar¨ªn-Pag¨¢n %A Emmanuelle Prost-Camus %A Jos¨¦ Miguel Rubio-P¨¦rez %A Julien Cases %A Linda H. Chung %A Michel Prost %A Pedro E. Alcaraz %A Sylvie Gaillet %J Archive of "Nutrients". %D 2017 %R 10.3390/nu9040421 %X Workout capacity is energy-production driven. To produce peak metabolic power outputs, the organism predominantly relies more on anaerobic metabolism, but this undoubtedly has a negative and limiting impact on muscle function and performance. The aim of the study was to evaluate if an innovative polyphenol-based food supplement, PerfLoad£¿, was able to improve metabolic homeostasis and physical performance during high-intensity exercises under anaerobic conditions. The effect of a supplementation has been investigated on fifteen recreationally-active male athletes during a randomized, double-blind and crossover clinical investigation. The Wingate test, an inducer of an unbalanced metabolism associated to oxidative stress, was used to assess maximum anaerobic power during a high-intensity exercise on a cycle ergometer. Supplementation with PerfLoad£¿ correlated with a significant increase in total power output (5%), maximal peak power output (3.7%), and average power developed (5%), without inducing more fatigue or greater heart rate. Instead, oxidative homeostasis was stabilized in supplemented subjects. Such results demonstrated that PerfLoad£¿ is a natural and efficient solution capable of, similarly to training benefits, helping athletes to improve their physical performance, while balancing their metabolism and reducing exercise-induced oxidative stress %K preworkout %K anaerobic power %K pulse pressure %K oxidative stress %K Wingate test %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409760/