%0 Journal Article
%T Are Temporal Differences in GDNF and NOS Isoform Induction Contributors to Neurodegeneration? A Fluorescence Microscopy-Based Study
%A Angelica Padilla
%A Brian J. Poindexter
%A Diane L. M. Hickson-Bick
%A Marie-Francoise Doursout
%A Mya C. Schiess
%A Roger J. Bick
%A Yangyan Liang
%J Archive of "The Open Neurology Journal".
%D 2016
%R 10.2174/1874205X01610010067
%X Specific factors in Parkinson¡¯s disease have become targets as to their protective and degenerative effects. We have demonstrated that cytokines and PD-CSF detrimentally affect microglia and astrocyte growth. While glial cell-derived neurotrophic factor (GDNF) has been recognized as a possible neuron-rescue agent, nitric oxide synthase (NOS) has been implicated in neurodegenerative processes
%K Endotoxin
%K Fluorescence microscopy
%K Glial derived neurotrophic factor
%K Neurodegeneration
%K Nitric oxide
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009294/