%0 Journal Article
%T A High-fat and High-Cholesterol Diet Potentiates Oxidative Damage in Hippocampus of Mice Lacking Apolipoprotein E
%A Mary Guaraldi
%A Thomas B. Shea
%J Archive of "The Open Neurology Journal".
%D 2018
%R 10.2174/1874205X01812010012
%X We examined genetic and dietary challenge on hippocampal oxidative damage. Mice expressing (ApoE+/+) or lacking apolipoprotein E (ApoE-/-) were maintained on a standard diet or a high fat /high cholesterol (challenge) diet for 11-31 weeks. Similar levels of oxidative species were observed for ApoE+/+ and -/- mice maintained on the basal diet
%K Oxidative damage
%K Latent oxidative damage
%K ApoE
%K Hippocampus
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838635/