%0 Journal Article
%T Robot-Embodied Neuronal Networks as an Interactive Model of Learning
%A Abraham M Shultz
%A Holly A. Yanco
%A Mary Guaraldi
%A Sangmook Lee
%A Thomas B. Shea
%J Archive of "The Open Neurology Journal".
%D 2017
%R 10.2174/1874205X01711010039
%X The reductionist approach of neuronal cell culture has been useful for analyses of synaptic signaling. Murine cortical neurons in culture spontaneously form an ex vivo network capable of transmitting complex signals, and have been useful for analyses of several fundamental aspects of neuronal development hitherto difficult to clarify in situ. However, these networks lack the ability to receive and respond to sensory input from the environment as do neurons in vivo. Establishment of these networks in culture chambers containing multi-electrode arrays allows recording of synaptic activity as well as stimulation
%K Multi-electrode array
%K Neuronal network
%K Cortical neuronal culture
%K Learning
%K Plasticity
%K Sensory input
%K Cybernetics
%K Manus robot arm
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678239/