%0 Journal Article %T Insights in Hypothesis Testing and Making Decisions in Biomedical Research %A Demosthenes B. Panagiotakos %A Varin Sacha %J Archive of "The Open Cardiovascular Medicine Journal". %D 2016 %R 10.2174/1874192401610010196 %X It is a fact that p values are commonly used for inference in biomedical and other social fields of research. Unfortunately, the role of p value is very often misused and misinterpreted; that is why it has been recommended the use of resampling methods, like the bootstrap method, to calculate the confidence interval, which provides more robust results for inference than does p value. In this review a discussion is made about the use of p values through hypothesis testing and its alternatives using resampling methods to develop confidence intervals of the tested statistic or effect measure %K Biostatistics %K Confidence intervals %K Evidence based medicine %K p value %K Resampling %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054503/