%0 Journal Article
%T Contrast-induced Encephalopathy Following Embolization of Intracranial Aneurysms in Hemodialysis Patients
%A Keisuke OTA
%A Noriaki MATSUBARA
%A Shigeru MIYACHI
%A Takashi IZUMI
%A Toshihiko WAKABAYASHI
%J Archive of "Neurologia medico-chirurgica".
%D 2017
%R 10.2176/nmc.oa.2017-0132
%X Contrast-induced encephalopathy is a very rare complication associated with endovascular treatment of intracranial aneurysms. Patients with renal dysfunction may be prone to developing contrast medium neurotoxicity as a result of delayed elimination of the contrast medium in renal metabolism. This article focuses on our experience with contrast-induced encephalopathy in patients with end-stage renal disease requiring hemodialysis. The authors retrospectively reviewed five patients diagnosed with contrast-induced encephalopathy who underwent aneurysm coil embolization at their institution from January 2006 to December 2015. During the 10-year period, embolization was performed in 755 cases, among which contrast-induced encephalopathy occurred in five patients (0.66%). Three of the five patients were undergoing dialysis for chronic renal failure (one male and two female; mean age 66.7). Embolization for hemodialysis patients was performed in eight during the same period and the incidence of contrast-induced encephalopathy in hemodialysis patients is quite high in our series (3 of 8; 38%). Procedures were performed in one for recurrence of unruptured anterior-communicating artery aneurysm and in two for unruptured basilar-tip aneurysm. Mean approximately 220 ml of contrast media was used among three hemodialysis patients. All three patients showed an improvement or a control in symptoms soon after hemodialysis. Recovery of neurological symptoms was complete in two and almost normal in one within 1 week after intervention. Contrast-induced encephalopathy should be kept in mind as an expected complication of aneurysm embolization in hemodialysis patients. In hemodialysis patients with contrast-induced encephalopathy, performing hemodialysis is an effective treatment to improve symptoms early
%K contrast-induced encephalopathy
%K embolization
%K intracranial aneurysm
%K hemodialysis
%K end-stage renal disease
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735227/