%0 Journal Article %T Evaluation of mast cells in oral premalignant and malignant lesions: A histochemical study %A Bhagwat Sharma %A Madhav Nagpal %A Rashmi Aggarwal %A Ruchieka Vij %A Shreya Singh %A Vineeta Gupta %J Archive of "National Journal of Maxillofacial Surgery". %D 2018 %R 10.4103/njms.NJMS_49_17 %X Oral leukoplakia, oral submucous fibrosis, and oral lichen planus are the precancerous or potentially malignant lesions and conditions whereas oral squamous cell carcinoma (OSCC) is a cancerous or malignant lesion of the oral cavity. They have characteristic clinical and histopathological features. These diseases not only originate from epithelium but also associated with chronic inflammation juxta-epithellialy. Mast cells present in the connective tissue stroma and release pro-inflammatory and mitogenic cytokines. These functions of mast cells contribute and enhance the pathogenesis translation of diseases %K Mast cells %K oral dysplasia %K oral squamous cell carcinoma %K toluidine blue %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251297/