%0 Journal Article %T Emerging role of precision medicine in biliary tract cancers %A Daniel H. Ahn %A James M. Bogenberger %A Mansi Arora %A Mitesh J. Borad %A Thomas T. DeLeon %J Archive of "NPJ Precision Oncology". %D 2018 %R 10.1038/s41698-018-0064-z %X Emerging role of precision medicine in biliary tract cancers. Yellow boxes highlight US FDA-approved drugs and drugs undergoing clinical investigation as reviewed, with arrows indicating pathway/target activation and blocked lines indicating pathway/target inhibition. BTC targets/pathways discussed are shown in color-coded boxes according to subcellular localization, blue£¿=£¿cell surface, orange£¿=£¿cytsolic, red£¿=£¿mitochondrial, and green£¿=£¿nuclear. ¡°¡ü¡± denotes over-expression, ¡°¦¤¡± denotes copy number abbreation and/or point mutation, a lighting bolt symbol denotes a synthetic lethal interaction between drug(s) and target(s) liste %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170410/