%0 Journal Article
%T Orexin Directly Enhances the Excitability of Globus Pallidus Internus Neurons in Rat by Co-activating OX1 and OX2 Receptors
%A Bin Li
%A He-Ren Gao
%A Jian-Jun Wang
%A Jing-Ning Zhu
%A Qian-Xing Zhuang
%A Xiao-Yang Zhang
%A Yi-Ting Zhong
%A Yong-Xiao Zhang
%A Zhang-Peng Chen
%J Archive of "Neuroscience Bulletin".
%D 2017
%R 10.1007/s12264-017-0127-0
%X Orexin-A excites two types of GPi neurons. A Diagram of rat brain in sagittal view showing the location of the GPi between 1.92 and 2.76 mm from bregma. B A coronal brain slice containing the GPi. C, D Electrophysiological identification of Types I and II neurons in the GPi and the effect of orexin-A. The diameters of both types were >20 ¦Ìm (arrowheads). Type I neurons showed a voltage sag during injection of a negative current step, whereas Type II neurons (n = 8, 10.5%) showed little or none. GPi, internal globus pallidus; ic, internal capsule
%K Orexin
%K OX1 receptor
%K OX2 receptor
%K Globus pallidus internus
%K Basal ganglia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567558/