%0 Journal Article
%T Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma
%A Ai-Wu Ke
%A Bi-Mang Fu
%A Chi Zhang
%A Dong-Mei Gao
%A Guo-Ming Shi
%A Hai-Xiang Sun
%A Hao Zou
%A Jia-Bin Cai
%A Jia-Cheng Lu
%A Li-Xin Liu
%A Lu Zhang
%A Nan Xie
%A Peng-Fei Zhang
%A Qiang Kang
%A Xiao-Yong Huang
%A Xin-Yu Zhang
%A Xuan Yang
%A Ying-Hao Shen
%A Zheng-Ji Song
%J Archive of "Cell Death & Disease".
%D 2017
%R 10.1038/s41419-017-0015-6
%X High expression of B7-H4 in tumor tissues of ICC patients. a qRT-PCR showed that the expression of B7-H4 mRNA in tumor tissues was higher than that in correspondingly peritumoral tissues (*p£¿<£¿0.05). b Representative image showed expression of B7-H4 protein in tumor samples and peritumoral tissues from 35 ICC patients by western blotting. c Semi-quantitative analysis showed that the expression of B7-H4 protein in tumors tissues was higher than that in peritumoral tissues(*p£¿<£¿0.05). d Representative image showed the expression of B7-H4 protein in tumor samples and peritumoral tissues from 140 ICC patients by immunohistochemical staining. e Semi-quantitaive analysis for IHC staining showed that B7-H4 protein expression in tumor samples was higher than that in peritumoral tissues (**p£¿<£¿0.01). f The expression of B7-H4 in tumor tissues from ICC patients with early recurrence after operation was higher than that in patients without recurrence (*p£¿<£¿0.05). g qRT-PCR from 35 ICC patients showed that the expression of B7-H4 mRNA in tumor tissues of ICC patients with early recurrence was much higher than that of patients without recurrence (***p£¿<£¿0.01). h Representative image showed expression of B7-H4 protein in 35 randomly selected ICC pateints by western blotting. i Semi-quantitaive analysis for western blotting showed that the expression of B7-H4 in tumor tissues from ICC patients with early recurrence was higher than that in patients without recurrence (**p£¿<£¿0.01
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870586/