%0 Journal Article %T Successful Endoscopic Management of Double Iatrogenic Perforations Induced by Endoscopic Retrograde Cholangiopancreatography and Computed Tomography-Guided Colon Drainage %A Jui-Hao Chen %A Kuang-En Chu %A Ping-Hsiu Wu %J Archive of "Case Reports in Gastroenterology". %D 2019 %R 10.1159/000495245 %X Endoscopic retrograde cholangiopancreatography (ERCP) is a high-risk procedure with a significantly high rate of complications, such as pancreatitis, bleeding, perforation, and infection. Pancreatitis is the most common post-ERCP complication with an incidence of approximately 3.5%. Although perforation is a rare complication with an incidence of 0.1¨C0.6%, it may be associated with a high rate of mortality of 1.0¨C1.5%. Here, we report a rare case of ERCP-induced double iatrogenic perforations in the duodenum and colon complicated by an intra-abdominal abscess. The post-ERCP perforation was successfully sealed using fibrin glue (Tisseel). The intra-abdominal abscess was treated with a computed tomography-guided pigtail drainage; however, the pigtail spontaneously migrated and perforated the ascending colon. The pigtail was removed, and closure of the colon perforation was successfully achieved with endoscopic clipping. Tisseel spray can be a treatment option for post-ERCP perforations. Careful consideration of procedural complications, early detection of perforations, and prompt treatment can be life-saving %K Endoscopic retrograde cholangiopancreatography %K Perforation %K Computed tomography-guided drainage %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381880/