%0 Journal Article
%T Vascularization converts the lineage fate of bone mesenchymal stem cells to endothelial cells in tissue-engineered bone grafts by modulating FGF2-RhoA/ROCK signaling
%A Bin Liu
%A Chunmei Wang
%A Donglin Li
%A Guoxian Pei
%A Huijie Jiang
%A Jimeng Wang
%A Junqin Li
%A Liu Yang
%A Pengzhen Cheng
%A Shuaishuai Zhang
%A Tianqing Cao
%A Yangjing Lin
%A Yi Gao
%A Yue Song
%J Archive of "Cell Death & Disease".
%D 2018
%R 10.1038/s41419-018-0999-6
%X Most cells were CD31- and CD11b/c- (a, left panel), and a further representative image shows that the percentage of the CD31-, CD11b/c- and CD45£¿ cells that express CD90 was 93.6% (a, right panel). b Multi-lineage differentiation assay of rat BMSCs: osteogenic, adipogenic and chondrogenic differentiation. c ¦Â-TCP scaffolds (5£¿mm in height and 4£¿mm in diameter, 70% porosity, 400£¿¦Ìm pore diameter) were incubated with GFP+ BMSCs for a week. d The femur bone defect was made in the left femur and fixed by internal fixation. After surgery, all rats were examined using X-ray imaging to confirm that the model was successful. e, f Two types of femur defect models were used: WT rats matched with GFP+ BMSCs-TEBGs and GFP+ rats matched with WT BMSCs-TEBG
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147920/