%0 Journal Article
%T Taurine attenuates arsenic-induced pyroptosis and nonalcoholic steatohepatitis by inhibiting the autophagic-inflammasomal pathway
%A Guang Yang
%A Jie Bai
%A Lei Yang
%A Liping Jiang
%A Ni Gao
%A Pei Pei
%A Rushan Yan
%A Sen Wei
%A Shuangyue Qi
%A Tianming Qiu
%A Xiance Sun
%A Xiaofang Liu
%A Xiaofeng Yao
%A Zhidong Wang
%J Archive of "Cell Death & Disease".
%D 2018
%R 10.1038/s41419-018-1004-0
%X a HE and Oil Red O staining of liver sections after As2O3 administration and pretreatment with Tau. Yellow arrows indicate steatosis. b¨Cd mRNA levels of lipid-associated genes in liver tissues after exposure to As2O3 and pretreatment with Tau, performed by qPCR. c F4/80 immunofluorescence staining of liver sections following As2O3 and Tau treatment. Yellow arrows indicate positive staining. e The content of triglyceride in mice livers. f The expression of liver inflammation-related proteins following exposure to As2O3 and Tau. The protein fraction was analyzed by western blot. g NAS in mouse livers. Values are mean£¿¡À£¿SD, and n£¿=£¿6. *P£¿<£¿0.05 compared with the control group, #P£¿<£¿0.05 compared with the 4£¿mg/L group; Scale bar£¿=£¿100£¿¦Ì
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148242/