%0 Journal Article
%T The role of the mitochondria and the endoplasmic reticulum contact sites in the development of the immune responses
%A Denis Martinvalet
%J Archive of "Cell Death & Disease".
%D 2018
%R 10.1038/s41419-017-0237-7
%X Mitochondrion (green) is juxtaposed with the endoplasmic reticulum (ER) (orange) forming an area of contact stabilized by molecular tethers, the nature of which determine the MERCs function. Matrix, mitochondrial matrix; IMM, inner mitochondrial membrane; MIS, mitochondrial intermembrane space; OMM, outer mitochondrial membrane; MCU, mitochondrial calcium uniporter; VDAC, voltage-dependent anion channel; Grp75, 75£¿kDa glucose-regulated protein; IP3R, inositol 1,4,5 three phosphate receptor; VAPB, vesicle-associated membrane protein-associated protein B; PTPIP51, protein tyrosine phosphatase-interacting protein 51; ERMES, ER-mitochondria encounter structure complex; MFN1 and 2, mitofusin 1 and 2; INF2, inverted formin 2; FIS1, Mitochondrial fission 1; Bap31, B-cell receptor-associated protein 31; MAVS, Mitochondrial antiviral-signaling protein; NLRP3, NOD-like receptors P3; TXNIP, thioredoxin-interacting protein; ASC, apoptosis-associated speck-like protein containing a CARD; ERp44, Endoplasmic reticulum resident protein and ERO1¦Á, oxidoreductin 1 ¦Á
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832423/