%0 Journal Article
%T bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
%A Dawei Sun
%A Derong Cui
%A Feng Ping
%A Wei Jiang
%A Wenying Wang
%A Xiaotao Xu
%A Xintao Wang
%A Yan Wang
%A Yu Du
%J Archive of "Cell Death & Disease".
%D 2018
%R 10.1038/s41419-017-0229-7
%X a Immunoblots of the apoptosis-related proteins cleaved Caspase-3 and Bcl-2. Total cell lysates from the hippocampus were used, and ¦Â-actin was used as an internal control. b Immunoblots of p53, Bax, and cytochrome c in the cytosolic and mitochondrial fractions. GAPDH was used as a loading control for cytosolic proteins, and COX IV was used as the loading control for mitochondrial proteins. c Immunoblots of the autophagy-related proteins LC3B and Beclin-1. Total cell lysates from the hippocampus were used. d¨Ck Densitometric analysis (mean£¿¡À£¿SEM, n£¿=£¿3 animals per group) of the proteins from (a, b, c) normalized to the respective loading controls. *P£¿<£¿0.05 vs. sham£¿+£¿vehicle, **P£¿<£¿0.01 vs. sham£¿+£¿vehicle, ***P£¿<£¿0.001 vs. sham£¿+£¿vehicl
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833346/