%0 Journal Article
%T Clinically Relevant Response to Cisplatin-5-Fluorouracyl in Intestinal-Type Sinonasal Adenocarcinoma with Loss of Vision: A Case Report
%A Ingele Casteels
%A Jonas Claus
%A Mark Jorissen
%A Paul M.J. Clement
%A Robert Hermans
%A Sandra Nuyts
%A Vincent Vander Poorten
%J Archive of "Case Reports in Oncology".
%D 2019
%R 10.1159/000499602
%X A 68-year-old man presented with rapid progressive visual loss caused by a progressive local invasive sinonasal intestinal-type adenocarcinoma (ITAC) with intracranial invasion. The local relapse of ITAC in the ethmoid sinus was previously treated with palliative radiotherapy and carboplatin-paclitaxel, without response, hence disease progression was seen. Ophthalmological examination revealed irreversible blindness of the left eye and a dramatic progressive visual loss of the right eye. Due to important visual loss caused by optic nerve invasion, a palliative treatment with cisplatin-5-fluorouracyl was started. This therapy resulted in a good clinical response with a regression of the local mass and a partial recovery of the vision
%K Intestinal-type sinonasal adenocarcinoma
%K Cisplatin-5-fluorouracyl
%K Systemic therapy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489020/