%0 Journal Article
%T STIL: a multi-function protein required for dopaminergic neural proliferation, protection, and regeneration
%A Aprell L. Carr
%A Congcong Liu
%A Lei Li
%J Archive of "Cell Death Discovery".
%D 2019
%R 10.1038/s41420-019-0172-8
%X a Normally, STIL binds SUFU, releases SUFU¡¯s suppression on GLI1, then GLI1 can be translocated to the nucleus for gene transcription. b When STIL is mutated, Shh down-stream signaling transduction cannot be completed because the SUFU-GLI1 heterodimers cannot enter the nucleus for gene transcription. (Modified from reference15
%K Cell death in the nervous system
%K Mechanisms of disease
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484007/