%0 Journal Article
%T Targeting autophagy potentiates antitumor activity of Met-TKIs against Met-amplified gastric cancer
%A Bin Dong
%A Dongshao Chen
%A Jianling Zou
%A Jing Gao
%A Lin Shen
%A Xiaojuan Wang
%A Xiaoting Lin
%A Zhi Peng
%A Zhongwu Li
%A Zuhua Chen
%J Archive of "Cell Death & Disease".
%D 2019
%R 10.1038/s41419-019-1314-x
%X a, b Met-amplified GC cells were treated with Met-TKIs as indicated and lysates were immunoblotted for proteins. c MKN45 cells were treated with PHA-665752 (PHA) 200£¿nM or SU11274 (SU) 1£¿¦ÌM for 36£¿h and LC3-positive puncta were counted by confocal immunofluorescence (autophagosomes were green and 4¡ä,6-diamidino-2-phenylindole (DAPI)-stained nuclei were blue). Scale bar, 5£¿¦Ìm. Data are expressed as median with interquartile range. *P£¿<£¿0.05 by nonparametric Mann¨CWhitney U-tes
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374362/