%0 Journal Article
%T Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice
%A AiHua Shen
%A Arpana Pandit
%A Dipendra Khadka
%A Eun-Young Cho
%A Gi-Su Oh
%A Hong-Seob So
%A Hyuk Shim
%A Hyung-Jin Kim
%A Raekil Park
%A Sei-Hoon Yang
%A Seon Young Kim
%A Seong-Kyu Choe
%A SeungHoon Lee
%A Su-Bin Lee
%A Subham Sharma
%A Tae Hwan Kwak
%J Archive of "Cell Death & Disease".
%D 2019
%R 10.1038/s41419-018-1252-z
%X a, b Pancreas injury was estimated by hematoxylin and eosin staining and a histologic damage score. Cont, saline (0.9% NaCl)-treated control group; CAE, 50£¿¦Ìg/kg caerulein-only group; CAE£¿+£¿Dun 10, caerulein plus 10£¿mg/kg dunnione combined group; CAE£¿+£¿Dun 20, caerulein plus 20£¿mg/kg dunnione combined group; CAE£¿+£¿Dun 40, caerulein plus 40£¿mg/kg dunnione combined group; Dun, 40£¿mg/kg dunnione-only group. Scale bar: 200£¿¦Ìm. c The pancreas-to-bodyweight ratio and serum amylase/lipase levels were measured. Each value represents the mean£¿¡À£¿SD (n£¿=£¿5). *P£¿<£¿0.05, **P£¿<£¿0.0
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315021/