%0 Journal Article
%T Hypoxia inducible factor 1¦Á in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment
%A Aijuan Qu
%A Baoqi Yu
%A Dan Qi
%A Frank J. Gonzalez
%A Guomin Xie
%A Huihua Li
%A Jie Du
%A Joseph Taranto
%A Ming Wei
%A Qingbo Xu
%A Shiyu Jiao
%A Xia Wang
%A Yan Duan
%A Yanting Song
%A Yatrik M. Shah
%A Ye Liu
%J Archive of "Cell Death & Disease".
%D 2019
%R 10.1038/s41419-019-1757-0
%X WT mice were infused with saline or 1000£¿ng/kg/min Ang II for 28 days. a Immunofluorescence analysis of representative cross-sections of mice aortas for HIF1¦Á (red) and ¦Á-SMA (green), nuclei was stained with DAPI. VSMCs were isolated form WT mice and treated with 1£¿¦ÌM Ang II for 24£¿h. b Hif1a mRNA was measured by qPCR analysis. c HIF1¦Á protein was detected by western blot. **P£¿<£¿0.01, ***P£¿<£¿0.001, n£¿=£¿3 per group, statistical significance was determined by the unpaired t-tes
%K Vascular diseases
%K Inflammation
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639417/