%0 Journal Article %T The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer %A Carleigh V. Frazier %A Jia Yu %A Judy C. Boughey %A Liewei Wang %A Matthew P. Goetz %A Reynold C. Ly %A Richard Weinshilboum %A Sisi Qin %A Xiao-Yang Fan %A Yongxian Zhuang %J Archive of "Cancer & Metabolism". %D 2019 %R 10.1186/s40170-018-0193-4 %X The online version of this article (10.1186/s40170-018-0193-4) contains supplementary material, which is available to authorized users %K Tumor protein D54 (TPD54) %K Pyruvate dehydrogenase (PDH) %K Pyruvate dehydrogenase kinase (PDK) %K Metformin %K Mitochondrial reactive oxygen species (ROS) %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345044/