%0 Journal Article %T A Case of Myxofibrosarcoma in an Unusual Thoracic Location %A Jose A. Rodriguez %A Kavitha Gopalratnam %A Kevin A. Woodson %A Robert Folman %J Archive of "Case Reports in Oncology". %D 2016 %R 10.1159/000442875 %X Myxofibrosarcoma is a soft tissue neoplasm composed of malignant fibroblasts with a myxoid matrix. It is commonly found in patients during their 6th through 8th decades of life with a slight male predominance. Myxofibrosarcomas are classified as low- to high-grade tumors that are differentiated by hypercellularity, variation of mitotic activity and degree of necrosis. The most common sites are the extremities (77%) and trunk (12%), with the retroperitoneum and mediastinum being very rare. In this case report, we describe a patient presenting with myxofibrosarcoma of the mediastinum, a rare site for the development of myxofibrosarcoma. This case of primary mediastinal myxofibrosarcoma appears to be only the second described in the English-language literature %K Myxofibrosarcoma %K Primary mediastinal myxofibrosarcoma %K Thoracic location %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748782/