%0 Journal Article
%T Atypical Endometrial Hyperplasia Arising in a Cesarean Section Scar: A Mechanism of Malignant Transformation
%A Andrzej Semczuk
%A Dorota Lewkowicz
%A Maciej J¨®£¿wik
%A Marek Gogacz
%A Marta Monist
%A Micha£¿ Bogusiewicz
%A Tomasz Rechberger
%J Archive of "Case Reports in Oncology".
%D 2019
%R 10.1159/000499760
%X The incidence of scar endometriosis in Cesarean sections varies between 0.03 and 0.4%. However, the recently increased rate of Cesarean sections worldwide may be causing an increase in occurrence of scar endometriosis. This report presents anatomopathological evidence of an early-stage malignant transformation in endometriotic tissue from a post-Cesarean scar and briefly reviews possible underlying mechanisms. A 40-year-old woman with a body mass index of 42.7 was referred to the gynecological department with recurrent pain and presence of a palpable mass in her Cesarean section scar. She had undergone this procedure 7 years earlier and began experiencing discomfort and pain at the incision site 6 months postoperatively. Surgical treatment was instituted with complete removal of the lesion. Anatomopathological examination revealed endometriotic tissue intertwined with atypical endometrial hyperplasia and fibrosis. At 2 years' follow-up, she was asymptomatic, both clinically and based on ultrasound examination. Endometriotic foci inoculated within an abdominal scar may undergo malignant transformation. Long-lasting abdominal scar endometriosis, in morbidly obese women, requires special attention from the physician
%K Atypical endometrial hyperplasia
%K Cesarean section
%K Endometriosis
%K Obesity
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514506/