%0 Journal Article
%T Long noncoding RNA PCAT1, a novel serum-based biomarker, enhances cell growth by sponging miR-326 in oesophageal squamous cell carcinoma
%A Baoen Shan
%A Dan Li
%A Jiao Chen
%A Lianmei Zhao
%A Lijie Huang
%A Qimin Zhan
%A Shujuan Shao
%A Wenzhong Liu
%A Xin Chen
%A Xin Dong
%A Xuefeng Liu
%A Yabing Zhao
%A Yali Wang
%A Yan Wang
%A Yongmei Song
%A Yu Wang
%A Yunping Ma
%A Zhengzheng Li
%J Archive of "Cell Death & Disease".
%D 2019
%R 10.1038/s41419-019-1745-4
%X a PCAT1 expression in 39 paired ESCC samples and adjacent normal tissues determined by RT-qPCR. ¦Â-actin was used as an internal reference. Statistical significance was assessed using the paired Student¡¯s t test. ***P£¿<£¿0.001. b Analysis of PCAT1 expression in ESCA (TCGA¡¯s abbreviation for oesophageal carcinoma) tissues and normal tissues by using the TCGA database. Statistical significance was assessed using the Mann-Whitney test. **P£¿<£¿0.01. c The expression of PCAT1 was detected in eight ESCC cell lines and two immortalized normal oesophageal epithelial cell lines (NE2 and NE3) by RT-qPCR. GAPDH was used as an internal reference. The expression of PCAT1 in NE2 cells was defined as 1. d RT-qPCR analysis of PCAT1 half-life in KYSE30 cells treated with actinomycin D. GAPDH was used as an internal referenc
%K Tumour biomarkers
%K Cell growth
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609620/