%0 Journal Article
%T TTF-1 Expression in Rectal Adenocarcinoma: A Case Report and Review of the Literature
%A Astrid Belalcazar
%A Uma Krishnamurti
%A Walid Shaib
%J Archive of "Case Reports in Oncology".
%D 2016
%R 10.1159/000450973
%X Thyroid transcription factor 1 (TTF-1) is considered a highly sensitive and specific marker for primary lung adenocarcinoma. However, in recent years retrospective studies of tumor samples have confirmed that, although rare, TTF-1 can also be expressed in colorectal adenocarcinoma. There are a few case reports of patients with TTF-1-positive colon adenocarcinoma in the medical literature but none of TTF-1-positive rectal adenocarcinoma. Here, we present a case of rectal adenocarcinoma with lung metastasis found to be TTF-1 positive on immunohistochemistry. A review and discussion of the available literature is also included
%K Colorectal cancer
%K Rectal cancer
%K Immunohistochemistry
%K TTF-1
%K TTF
%K Thyroid transcription factor
%K Rectal adenocarcinoma
%K Colorectal adenocarcinoma
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156892/