%0 Journal Article
%T Neutrophil extracellular traps induced by VP1 contribute to pulmonary edema during EV71 infection
%A Fan Hu
%A Huijuan Wang
%A Jiandong Sun
%A Juan Xu
%A Linfu Zhou
%A Mingshun Zhang
%A Nan Wang
%A Qiyun Ma
%A Xiaofan Yang
%A Zhengxia Wang
%A Zhixiao Sun
%A Zhongqi Chen
%A Zibin Wang
%J Archive of "Cell Death Discovery".
%D 2019
%R 10.1038/s41420-019-0193-3
%X a The effects of VP1 on pulmonary edema were determined by the wet-to-dry (W/D) lung weight ratio 4£¿h after VP1 intranasally administered. b Relative mRNA expression (log2) of inflammatory cytokines (TNF-¦Á, IL-1¦Â, and IL-6) in lungs was determined by qRT-PCR. c Representative images of H&E©\stained lung sections for the analysis of inflammatory cell infiltration and pulmonary edema; magnification, ¡Á200; scale bar, 100£¿¦Ìm. The data are shown as the mean£¿¡À£¿SEM. n£¿=£¿3¨C5 per group. *p£¿<£¿0.05, **p£¿<£¿0.01, ***p£¿<£¿0.000
%K Immune cell death
%K Viral infection
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609695/