%0 Journal Article
%T Sirt6-induced autophagy restricted TREM-1-mediated pyroptosis in ox-LDL-treated endothelial cells: relevance to prognostication of patients with acute myocardial infarction
%A Chen Fei
%A Guan Chun-Yu
%A Hou Han-Jin
%A Ji Bing
%A Lai Yan
%A Lin Hao
%A Liu Xue-Bo
%A Ping Fan
%A Tang Jia-Ni
%A Tong Jing
%A Yao Yi-An
%A Ye Zi
%J Archive of "Cell Death Discovery".
%D 2019
%R 10.1038/s41420-019-0168-4
%X a Confocal detection of ox-LDL-induced pyroptotic cells formation. LDL was used as a negative control, and LPS as a positive control. Green: 488-labeled Casp1; red: TMR red-labeled pyroptotic nucleus; blue: DAPI-labeled natural nucleus; green and red double-labeled cells correspond to pyroptotic cells. N£¿=£¿3. Scale bar: 50£¿¦Ìm. b Flow cytometry detecting ox-LDL-induced pyroptotic cells percentage. N£¿=£¿3; *p£¿<£¿0.05 versus LDL group. c. Flow cytometry detection of ox-LDL-induced EMPs number. N£¿=£¿3; *p£¿<£¿0.05 versus LDL group. d RT-PCR detection of mRNA expression of ox-LDL-induced inflammatory factors. N£¿=£¿3; *p£¿<£¿0.05 versus LDL grou
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461678/