%0 Journal Article %T Long-term Effect of Injection Treatment for Osteoarthritis in the Knee by Orthokin Autologous Conditioned Serum %A Danial Zarringam %A Daniel B. F. Saris %A Joris E. J. Bekkers %J Archive of "Cartilage". %D 2018 %R 10.1177/1947603517743001 %X Orthokin is an intra-articular autologous conditioned serum (ACS). Its use might have a beneficial biological effect on pain and function of osteoarthritis in the knee. However, earlier studies lack any consensus on its clinical application and disease modifying effect %K osteoarthritis %K Orthokin %K interleukin-1 %K disease-modifying osteoarthritis drugs %K placebo %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871127/