%0 Journal Article %T Dexmedetomidine to control signs associated with lisdexamfetamine dimesylate toxidrome in a cat %A Charlotte Means %A Christopher L. Norkus %A Iain Keir %J Archive of "The Canadian Veterinary Journal". %D 2017 %X A 5-month-old intact female domestic shorthaired cat had mydriasis, agitation, and increased locomotion after ingestion of lisdexamfetamine, 10.3 mg/kg body weight (BW). Despite treatment with IV fluids, IV acepromazine, oral cyproheptadine and intravenous lipid emulsion the patient¡¯s clinical signs worsened. Dexmedetomidine administered at 2 ¦̀g/kg BW and continued at 0.5 ¦̀g/kg BW per hour rapidly controlled the patient¡¯s signs. An episode of vomiting and hematuria developed. Follow-up 5 days after discharge revealed that the cat appeared normal %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302200/