%0 Journal Article %T The design of high affinity human PD-1 mutants by using molecular dynamics simulations (MD) %A Chuchu Wang %A Jiangfeng Du %A Wenjie Zhai %A Wenshan Zhao %A Yahong Wu %A Yanfeng Gao %A Yaping Qin %A Yuanming Qi %J Archive of "Cell Communication and Signaling : CCS". %D 2018 %R 10.1186/s12964-018-0239-9 %X The online version of this article (10.1186/s12964-018-0239-9) contains supplementary material, which is available to authorized users %K Molecular dynamics simulations %K Mutagenesis %K PD-1 %K Binding energy %K Drug design %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992718/