%0 Journal Article
%T E1A oncogene induced sensitization to NK cell induced apoptosis requires PIDD and Caspase-2
%A James L. Cook
%A Jay R. Radke
%A John M. Routes
%J Archive of "Cell Death Discovery".
%D 2019
%R 10.1038/s41420-019-0189-z
%X a [Cr51]-labeled MCA102 (circle), MCA102 E1A (triangle) cells were incubated with RNK-16 cells at the indicated RNK:target ratios in the absence or presence (inverted triangle) of 100£¿¦ÌM zVAD-fmk. After 6£¿h, supernatants were collected and % specific Cr51 release was assessed (mean£¿¡À£¿SEM; n£¿=£¿4, ***P£¿<£¿0.0001, **P£¿¡Ü£¿0.0084, one-way ANOVA). b [Cr51]-labeled BMK (circle) or BMK-E1A (triangle) cells were incubated with RNK-16 cells at the indicated RNK:target ratios in the absence or presence (inverted triangle) of 100£¿¦ÌM zVAD-fmk. After 6£¿h, supernatants were collected and % specific Cr51 release was assessed (mean£¿¡À£¿SEM; n£¿=£¿4, ***P£¿¡Ü£¿0.0001, one-way ANOVA
%K Innate immunity
%K Apoptosis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602934/