%0 Journal Article
%T Curcumin induced oxidative stress causes autophagy and apoptosis in bovine leucocytes transformed by Theileria annulata
%A Anand Srivastava
%A Prasanna Babu Araveti
%J Archive of "Cell Death Discovery".
%D 2019
%R 10.1038/s41420-019-0180-8
%X a percentage of growth inhibition upon treating infected cells with various concentrations (1, 2.5, 5, 10 and 20£¿¦ÌM) of curcumin at various time points (12, 24 and 36£¿h), b Absorbance of curcumin in methanolic extract of Ana2014 cells. Red line indicates the absorbance in the curcumin treated cells and green line indicates the absorbance in untreated cells, c TUNEL assay representing DNA fragmentation induced by curcumin. (i) unstained, (ii) untreated, (iii) 20£¿¦ÌM, (iv) 40£¿¦ÌM and (v) 80£¿¦ÌM, d Annexin V FITC- PI staining of untreated and 20£¿¦ÌM curcumin treated Ana2014 cells for 24£¿h, showing the percentage of live, early apoptotic, apoptotic and necrotic cell population. N£¿=£¿3. Data are presented as mean£¿¡À£¿SD. * represents p£¿<£¿0.05, ** represents p£¿<£¿0.01, and *** represents p£¿<£¿0.001, compared with the untreated grou
%K Antiparasitic agents
%K Parasitic infection
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547749/