%0 Journal Article
%T Genetic variation may confound analysis of CRISPR-Cas9 off-target mutations
%A Guanqun Wang
%A Jianbin Wang
%A Meijie Du
%A Ting F. Zhu
%J Archive of "Cell Discovery".
%D 2018
%R 10.1038/s41421-018-0025-2
%X a Venn diagrams displaying the number of SNVs (left) or indels (right) identified in the CRISPR-edited animal and control mice. B6-1, B6-2, and B6-3: C57BL/6J control mice. CRISPR-edited: Zkscan1+/£¿ mouse. b Heat maps showing the number of SNV (green) and indel (purple) sites at which the experimental mice have different genotypes compared with each other. c Number of SNV or indel sites located at 3-bp upstream from an NGG sequence (on both strands
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902475/