%0 Journal Article
%T Decreased IL-17RB expression impairs CD11b+CD11c£¿ myeloid cell accumulation in gastric mucosa and host defense during the early-phase of Helicobacter pylori infection
%A Bin Han
%A Chuan-jie Hao
%A Fang-yuan Mao
%A Hui Kong
%A Jia Han
%A Jin-yu Zhang
%A Liu-sheng Peng
%A Ping Cheng
%A Qiang Ma
%A Quan-ming Zou
%A Shi-ming Yang
%A Ting-ting Wang
%A Weisan Chen
%A Xian-hua Chen
%A Yi-pin Lv
%A Yong-sheng Teng
%A Yu-gang Liu
%A Yuan Zhuang
%J Archive of "Cell Death & Disease".
%D 2019
%R 10.1038/s41419-019-1312-z
%X a IL-17RB mRNA expression in gastric mucosa of H. pylori-infected (n£¿=£¿80) and uninfected donors (n£¿=£¿16) were compared. b The correlation between IL-17RB mRNA expression and H. pylori colonization in gastric mucosa of H. pylori-infected donors was analyzed. c IL-17RB mRNA expression in gastric mucosa of uninfected (n£¿=£¿16), cagA+ H. pylori-infected (n£¿=£¿67), cagA£¿ and H. pylori-infected (n£¿=£¿13) donors was compared. d Dynamic changes of IL-17RB mRNA expression and IL-17RB mRNA expression on day 7 or 9 p.i. in gastric mucosa of WT H. pylori-infected, ¦¤cagA-infected, and uninfected mice. n£¿=£¿5 per group per time point in (d). e IL-17RB protein in gastric mucosa of WT H. pylori-infected, ¦¤cagA-infected, and uninfected mice on day 9 p.i. were analyzed by IHC. Scale bars: 100£¿¦Ìm. f IL-17RB protein in gastric mucosa of WT H. pylori-infected, ¦¤cagA-infected, and uninfected mice on day 9 p.i. were analyzed by Western blot. g IL-17RB mRNA expression or IL-17RB protein in WT H. pylori-infected, ¦¤cagA-infected, and uninfected isolated primary gastric mucosa tissues (MOI£¿=£¿100, 24£¿h) from uninfected donors were compared (n£¿=£¿3) analyzed by real time PCR or Western blot. *P£¿<£¿0.05, ** P£¿<£¿0.01, n.s P£¿>£¿0.05 for groups connected by horizontal lines compared, or compared with uninfected mic
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349840/