%0 Journal Article
%T Recommendations and Choices for BRCA Mutation Carriers at Risk for Ovarian Cancer: A Complicated Decision
%A Amber M. Klimczak
%A Karen H. Lu
%A Kelsey E. Lewis
%A Samuel C. Mok
%J Archive of "Cancers".
%D 2018
%R 10.3390/cancers10020057
%X Current ovarian cancer screening guidelines in high-risk women vary according to different organizations. Risk reducing surgery remains the gold standard for definitive treatment in BRCA mutation carriers, but research advancements have created more short-term options for patients to consider. The decisions involved in how a woman manages her BRCA mutation status can cause a great deal of stress and worry due to the imperfect therapy options. The goal of this review was to critically analyze the screening recommendations and alternative options for high-risk ovarian cancer patients and evaluate how these discrepancies and choices affect a womanĄŻs management decisions
%K BRCA
%K ovarian cancer
%K risk-reducing surgery
%K CA-125
%K screening guidelines
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836089/