%0 Journal Article %T Sumoylation of Notch1 represses its target gene expression during cell stress %A Cecilia Sahlgren %A Christian J. M. Antila %A Henri A. Blomster %A Johan Holmberg %A K£¿the M. Dahlstr£¿m %A Lea Sistonen %A Tiina A. Salminen %A Vilma Rraklli %J Archive of "Cell Death and Differentiation". %D 2018 %R 10.1038/s41418-017-0002-6 %X Notch as a sumoylation target protein. a The sequence around the putative sumoylation site K1774/K1780/K1781/K1782 is located in the intracellular domain of Notch. b Sequence alignment of the Notch1 region surrounding the putative sumoylation site K1780 using the Clustal Omega web-based tool. The putative sumoylation site is highlighted in gra %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864205/